Professor Brian Cox takes a celebrity audience through the most challenging concepts in physics from the lecture theatre of the Royal Institution of Great Britain. With the help of fellow scientist Jim Al-Khalili and guests Simon Pegg, Sarah Millican, James May and Jonathan Ross, he shows how diamonds are made up of nothingness, and how one such precious gem in the heart of London is in communication with the largest diamond in the cosmos. He also reveals how things can be in two places at once and why everything that people can see and touch in the universe actually exists.